INTERLEUKIN-27 IS A POTENT INHIBITOR OF CIS HIV-1 REPLICATION IN MONOCYTE-DERIVED DENDRITIC CELLS VIA A TYPE I INTERFERON-INDEPENDENT PATHWAY.

Interleukin-27 is a potent inhibitor of cis HIV-1 replication in monocyte-derived dendritic cells via a type I interferon-independent pathway.

IL-27, a member of the IL-12 family of cytokines, plays an important and diverse role in the function of the immune system.Whilst generally recognized as an anti-inflammatory cytokine, in addition IL-27 has been found to have broad anti-viral effects.Recently, IL-27 has been shown to be a potent inhibitor of HIV-1 infection in CD4+ T cells and macr

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Spinal cord injury in an adult patient with thoracic butterfly vertebra: a case report and review of the literature

Abstract Background Butterfly vertebrae are a rare congenital vertebral anomaly.An overlap of this spinal anomaly with other diseases has been reported.However, to the authors’ knowledge, the coexistence of butterfly vertebrae and spinal cord injury has not been reported in the literature.Case presentation A 42-year-old male was admitted to our e

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